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Principal Scientist

Date: Aug 5, 2022

Location: West Chester, Pennsylvania, US, 19380

Company: Teva Pharmaceuticals

Company Info

Teva is a global pharmaceutical leader and the world's largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world's largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we've built a promising pipeline centered around our core therapeutic areas.  We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!

Job Description

As a Principal Scientist - Bioassays and Biosciences in the Analytical Sciences Operations department at Teva,  the candidate will be responsible for managing the development and implementation of cell-based and ligand binding assays, and be a recognized subject matter expert for these methods.  The position also provides the opportunity to contribute to strategic planning for product characterization assessments; and work with cross-functional team to advance biologic drug development at Teva's West Chester location.

We are looking for a candidate with demonstrated expertise in the development of ELISA and cell-based potency functional assays. The successful candidate may manage one or more analysts and will provide scientific input and broad method knowledge for stage appropriate development of methods which mimics a drug candidate mechanism of action. 

The successful candidate will be responsible for managing assay design/controls, troubleshooting, data evaluation, method qualifications and sample testing to support regulatory submissions for Teva’s broad portfolio of biologic drug candidates.  The candidate should have experience in a variety of cell methods and technologies for assessment of potency (e.g. cell proliferation, cell signaling, cytokine expression) and effector function (e.g. ADCC and CDC assays). A knowledge of transient/stable cell line generation and/or flow cytometry, cell sorting, or profiling cell responses to ligands is preferred.

In this role you may be responsible for successful management of one or more technical analysts, including day to day activities, training, and career development.  The candidate will work closely with Analytical Sciences, CMC, and project managers as a departmental project representative.  The position requires the ability to deliver characterization methods for biologics drug candidates against project deadlines and aptitude to provide strategic input on biologic project development. 


Other duties:

  • Responsible for authorship and/or review of SOPs, development reports, qualification protocols and reports, and contribute to authorship of regulatory submission documents.
  • Responsible for assessing and meeting project timelines. 
  • May oversee aspects of technology transfer to internal and external sites and engage, support, and review work conducted at CROs.  
  • May engage in long-range project or technological planning and assist in developing budgets for capital expenditures and contracts. 
  • Familiarity with GMP potency assay compliance requirements and procedures a plus.


  • PhD degree in Biochemistry, Cell Biology or other life sciences related field of study
  • At least 7 years of experience in pharmaceutical industry developing cell-based functional assays
  • At least 2 years of experience in directing/ managing scientific team


Research & Development

Sub Function

Biological Research

Reports To

Laurie Pukac

Already Working @TEVA?

If you are a current Teva employee, please apply using the internal career site available on "Employee Central". By doing so, your application will be treated with priority. You will also be able to see opportunities that are open exclusively to Teva employees. Use the following link to search and apply: Internal Career Site

The internal career site is available from your home network as well. If you have trouble accessing your EC account, please contact your local HR/IT partner.

Teva’s Equal Employment Opportunity Commitment

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws.

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