Share this Job

Vice President Translational & Precision Medicine

Date: Nov 21, 2022

Location: Philadelphia, US, 1111

Company: Teva Pharmaceuticals

Who are we?

Teva is a global pharmaceutical leader and the world's largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world's largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we've built a promising pipeline centered around our core therapeutic areas.  We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!

Job Description

The Vice President will lead the TPM division and while collaborating with all relevant functions independently design and implement TM strategies to enhance probability of success for clinical programs.  This role is part of the Innovative Medicines  Leadership Team and plays a critical role in the overall Innovative Medicines  strategy.  In addition, the Head of TPM will lead and manage TPM programmatic initiatives and entitlements, including (but not limited to) the Indication Assessment Authority and the Biosample Storage Program.

The Head of TPM will develop and execute biomarker discovery and development research initiatives associating genomic, device/digital and other biomarkers with drug response (including responder population identification), safety and/or compliance. The Head of TPM will advise R&D functions as an expert in all TPM-related aspects of science, medicine, regulatory strategy, intellectual property (IP), assay development, commercial value, etc. This role will provide expert support and leadership  in the evaluation of in-licensing compound and collaboration opportunities. The Head of TPM will work closely in collaboration with various development functions to identify opportunities to enhance candidate selection and to develop comprehensive TPM scientific plans for candidates selected to move into clinical development, including further development of these plans throughout the life cycle of the compound. The incumbent will design translational strategies and biomarker studies, composing the relevant documentation and being accountable for its on-time execution.

This role can be based in either West Chester PA USA or Israel

Responsibilities:

  • Lead the TPM team, whilst collaborating closely with the SVP of Innovative Medicines and other members of the Innovative Medicines Leadership Team on strategy and management. Oversee TPM resources to ensure project teams receive translational medicine plans, oversight of sample collection, handling, analysis and data interpretation.
  • Participate in the SRD, in which representatives of relevant functions and external capability and capacity providers collaborate to identify and prioritize multiple potential indications for clinical development of single therapeutic entities.
  • Provide support and leadership for the selection, planning and execution of Phase 0 and Phase 1b trials executed by the TRD division.
  • Independently and innovatively design and implement TPM strategies effectively to enhance probability of success for all clinical programs in collaboration with other relevant functions.
  • Advise TA and other relevant R&D functions as an expert in all TPM-related aspects of science, medicine, regulatory strategy, intellectual property (IP), assay development, commercial value, etc., providing expert support for the evaluation of in-licensing compound and collaboration opportunities.
  • Work closely in collaboration with TA leadership to enhance candidate selection and to develop comprehensive TM scientific plans for each of the prioritized candidates selected to move into clinical development, further developing these plans throughout the life cycle of the compound.
  • Rapidly access relevant in silico data from a wide variety of external sources for internal decision making to inform biomarker strategies and facilitate the interpretation of results.

Qualifications

  • Experience in biomarker-related and/or assay-development-related scientific research and drug discovery/development (7-10+ years highly preferred).
  • Experience managing direct reports (PhD, MS, BS) and leading non-reporting teams.
  • Pre-clinical development; project management/leadership preferred.
  • Knowledgeable (and recognized as a leader) in biomarker sciences and translational medicine.
  • Deep proficiency in accessing, searching, querying and downloading data and/or information from various externally available public databases (NCBI, dbGAP, KEGG, OMIM, etc.) for rapid retrieval of key information relevant to PMP and biomarker study design and results interpretation.
  • Publication record or industry experience in fields associated with TPM and/or biomarkers.

 

Education:

  • M.D. plus Ph.D. in relevant areas such as Physiology, Pharmacology, Molecular Biology, Biochemistry, Genetics or Related Disciplines.

 

Travel Requirements:

  • Ability to travel approximately 10-15 % of the time

Function

Research & Development

Sub Function

Clinical Development

Reports To

Senior Vice President, Specialty R&D

 

Competencies

Already Working @TEVA?

If you are a current Teva employee, please apply using the internal career site available on "Employee Central". By doing so, your application will be treated with priority. You will also be able to see opportunities that are open exclusively to Teva employees. Use the following link to search and apply: Internal Career Site

The internal career site is available from your home network as well. If you have trouble accessing your EC account, please contact your local HR/IT partner.

Teva’s Equal Employment Opportunity Commitment

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws.